Publikationer SÅE

1: Grahnén A, Jansson B, Brundin RM, Ling-Andersson A, Lönnebo A, Johansson M,
Eckernäs SA. A dose-response study comparing suppression of plasma cortisol
induced by fluticasone propionate from Diskhaler and budesonide from Turbuhaler.
Eur J Clin Pharmacol. 1997;52(4):261-7. PubMed PMID: 9248762.


2: Bergström M, Westerberg G, Németh G, Traut M, Gross G, Greger G,
Müller-Peltzer H, Safer A, Eckernäs SA, Grahnér A, Långström B. MAO-A inhibition
in brain after dosing with esuprone, moclobemide and placebo in healthy
volunteers: in vivo studies with positron emission tomography. Eur J Clin
Pharmacol. 1997;52(2):121-8. PubMed PMID: 9174681.


3: Lönnebo A, Grahnén A, Jansson B, Brundin RM, Ling-Andersson A, Eckernäs SA. An
assessment of the systemic effects of single and repeated doses of inhaled
fluticasone propionate and inhaled budesonide in healthy volunteers. Eur J Clin
Pharmacol. 1996;49(6):459-63. PubMed PMID: 8706770.


4: Paintaud G, Alván G, Eckernäs SA, Wakelkamp M, Grahnén A. The influence of
food intake on the effect of two controlled release formulations of furosemide.
Biopharm Drug Dispos. 1995 Apr;16(3):221-32. PubMed PMID: 7787134.


5: Grahnén A, Eckernäs SA, Brundin RM, Ling-Andersson A. An assessment of the
systemic activity of single doses of inhaled fluticasone propionate in healthy
volunteers. Br J Clin Pharmacol. 1994 Dec;38(6):521-5. PubMed PMID: 7888290;
PubMed Central PMCID: PMC1364915.


6: Nived O, Sturfelt G, Eckernäs SA, Singer P. A comparison of 6 months'
compliance of patients with rheumatoid arthritis treated with tenoxicam and
naproxen. Use of patient computer data to assess response to treatment. J
Rheumatol. 1994 Aug;21(8):1537-41. PubMed PMID: 7983661.


7: Grahnén A, Olsson B, Johansson G, Eckernäs SA. Doxycycline carrageenate--an
improved formulation providing more reliable absorption and plasma concentrations
at high gastric pH than doxycycline monohydrate. Eur J Clin Pharmacol.
1994;46(2):143-6. PubMed PMID: 8039533.


8: Eckernäs SA, Roos BE, Kvidal P, Eriksson LO, Block GA, Neafus RP, Haigh JR.
The effects of simvastatin and pravastatin on objective and subjective measures
of nocturnal sleep: a comparison of two structurally different HMG CoA reductase
inhibitors in patients with primary moderate hypercholesterolaemia. Br J Clin
Pharmacol. 1993 Mar;35(3):284-9. PubMed PMID: 8471404; PubMed Central PMCID:
PMC1381576.


9: Leenders K, Hartvig P, Forsgren L, Holmgren G, Almay B, Eckernäs SA, Lundqvist
H, Långström B. Striatal [11C]-N-methyl-spiperone binding in patients with focal
dystonia (torticollis) using positron emission tomography. J Neural Transm Park
Dis Dement Sect. 1993;5(2):79-87. PubMed PMID: 8101445.


10: Alván G, Paintaud G, Eckernäs SA, Grahnén A. Discrepancy between
bioavailability as estimated from urinary recovery of frusemide and total
diuretic effect. Br J Clin Pharmacol. 1992 Jul;34(1):47-52. PubMed PMID: 1633067;
PubMed Central PMCID: PMC1381374.


11: Grahnén A, Lönnebo A, Beck O, Eckernäs SA, Dahlström B, Lindström B.
Pharmacokinetics of ketotifen after oral administration to healthy male subjects.
Biopharm Drug Dispos. 1992 May;13(4):255-62. PubMed PMID: 1600111.


12: Grahnén A, Eckernäs SA, Collin C, Ling-Andersson A, Tiger G, Nilsson M.
Comparative multiple-dose pharmacokinetics of controlled-release levodopa
products. Eur Neurol. 1992;32(6):343-8. PubMed PMID: 1490503.


13: Eckernäs SA, Grahnén A, Nord CE. Impact of dirithromycin on the normal oral
and intestinal microflora. Eur J Clin Microbiol Infect Dis. 1991
Aug;10(8):688-92. PubMed PMID: 1748127.


14: Grahnén A, Wennerlund P, Dahlström B, Eckernäs SA. Inter- and intraindividual
variability in the concentration-effect (sedation) relationship of flunitrazepam.
Br J Clin Pharmacol. 1991 Jan;31(1):89-92. PubMed PMID: 2015176; PubMed Central
PMCID: PMC1368417.


15: de Vries MH, de Koning P, Floot HL, Grahnén A, Eckernäs SA, Raghoebar M,
Dahlström B, Ekman L. Dose-proportionality of eltoprazine. Pharmacokinetics of
single oral doses in healthy subjects. Eur J Clin Pharmacol. 1991;41(5):485-8.
PubMed PMID: 1761079.


16: Nord CE, Grahnen A, Eckernäs SA. Effect of loracarbef on the normal
oropharyngeal and intestinal microflora. Scand J Infect Dis. 1991;23(2):255-60.
PubMed PMID: 1853174.


17: Karlsson MO, Dahlström B, Eckernäs SA, Johansson M, Alm AT. Pharmacokinetics
of oral noscapine. Eur J Clin Pharmacol. 1990;39(3):275-9. PubMed PMID: 2257866.


18: Andersson U, Eckernäs SA, Hartvig P, Ulin J, Långström B, Häggström JE.
Striatal binding of 11C-NMSP studied with positron emission tomography in
patients with persistent tardive dyskinesia: no evidence for altered dopamine D2
receptor binding. J Neural Transm Gen Sect. 1990;79(3):215-26. PubMed PMID:
2137000.


19: Hartvig P, Eckernäs SA, Lindberg BS, Lundqvist H, Antoni G, Rimland A,
Långström B. Regional distribution of the opioid receptor agonist
N-(methyl-11C)pethidine in the brain of the rhesus monkey studied with positron
emission tomography. Pharmacol Toxicol. 1990 Jan;66(1):37-40. PubMed PMID:
2155415.


20: Wallin A, Alafuzoff I, Carlsson A, Eckernäs SA, Gottfries CG, Karlsson I,
Svennerholm L, Winblad B. Neurotransmitter deficits in a non-multi-infarct
category of vascular dementia. Acta Neurol Scand. 1989 May;79(5):397-406. PubMed
PMID: 2568069.


21: Lundberg T, Lindström LH, Hartvig P, Eckernâs SA, Ekblom B, Lundqvist H,
Fasth KJ, Gullberg P, Långström B. Striatal and frontal cortex binding of
11-C-labelled clozapine visualized by positron emission tomography (PET) in
drug-free schizophrenics and healthy volunteers. Psychopharmacology (Berl).
1989;99(1):8-12. PubMed PMID: 2528781.


22: Hartvig P, Eckernäs SA, Ekblom B, Lindström L, Lundqvist H, Axelsson S, Fasth
KJ, Gullberg P, Långström B. Receptor binding and selectivity of three
11C-labelled dopamine receptor antagonists in the brain of rhesus monkeys studied
with positron emission tomography. Acta Neurol Scand. 1988 Apr;77(4):314-21.
PubMed PMID: 3260438.


23: Leenders KL, Aquilonius SM, Bergström K, Bjurling P, Crossman AR, Eckernas
SA, Gee AG, Hartvig P, Lundqvist H, Långström B, et al. Unilateral MPTP lesion in
a rhesus monkey: effects on the striatal dopaminergic system measured in vivo
with PET using various novel tracers. Brain Res. 1988 Mar 29;445(1):61-7. PubMed
PMID: 3259152.


24: Danielsson E, Eckernäs SA, Westlind-Danielsson A, Nordström O, Bartfai T,
Gottfries CG, Wallin A. VIP-sensitive adenylate cyclase, guanylate cyclase,
muscarinic receptors, choline acetyltransferase and acetylcholinesterase, in
brain tissue afflicted by Alzheimer's disease/senile dementia of the Alzheimer
type. Neurobiol Aging. 1988 Mar-Apr;9(2):153-62. PubMed PMID: 2897639.


25: Aquilonius SM, Bergström K, Eckernäs SA, Hartvig P, Leenders KL, Lundquist H,
Antoni G, Gee A, Rimland A, Uhlin J, et al. In vivo evaluation of striatal
dopamine reuptake sites using 11C-nomifensine and positron emission tomography.
Acta Neurol Scand. 1987 Oct;76(4):283-7. PubMed PMID: 2961191.


26: Eckernäs SA, Aquilonius SM, Hartvig P, Hägglund J, Lundqvist H, Någren K,
Långström B. Positron emission tomography (PET) in the study of dopamine
receptors in the primate brain: evaluation of a kinetic model using
11C-N-methyl-spiperone. Acta Neurol Scand. 1987 Mar;75(3):168-78. PubMed PMID:
3495092.


27: Hägglund J, Aquilonius SM, Eckernäs SA, Hartvig P, Lundquist H, Gullberg P,
Långström B. Dopamine receptor properties in Parkinson's disease and Huntington's
chorea evaluated by positron emission tomography using 11C-N-methyl-spiperone.
Acta Neurol Scand. 1987 Feb;75(2):87-94. PubMed PMID: 2953165.


28: Hägglund J, Aquilonius SM, Bergström K, Eckernäs SA, Hartvig P, Lundqvist H,
Långström B, Malmborg P, Någren K. Regional kinetics of [11C]methylspiperone in
the brain studied by positron emission tomography in patients with Parkinson's
disease. Adv Neurol. 1987;45:99-101. PubMed PMID: 2950732.


29: Aquilonius SM, Askmark H, Eckernäs SA, Gillberg PG, Hilton-Brown P, Rydin E,
Stålberg E. Cholinesterase inhibitors lack therapeutic effect in amyotrophic
lateral sclerosis. A controlled study of physostigmine versus neostigmine. Acta
Neurol Scand. 1986 Jun;73(6):628-32. PubMed PMID: 3529799.


30: Hartvig P, Lindquist NG, Aquilonius SM, d'Argy R, Bergström K, Bondesson U,
Eckernäs SA, Gullberg P, Larsson BS, Lindberg B, et al. Distribution of
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in experimental animals studied by
postiron emission tomography and whole body autoradiography. Life Sci. 1986 Jan
6;38(1):89-97. PubMed PMID: 3484535.


31: Hartvig P, Eckernäs SA, Lindström L, Ekblom B, Bondesson U, Lundqvist H,
Halldin C, Någren K, Långström B. Receptor binding of N-(methyl-11C) clozapine in
the brain of rhesus monkey studied by positron emission tomography (PET).
Psychopharmacology (Berl). 1986;89(2):248-52. PubMed PMID: 3088645.


32: Häggström JE, Sjöquist B, Eckernäs SA, Ingvast A, Gunne LM. Discrete regional
distribution of biochemical markers for the dopamine, noradrenaline, serotonin,
GABA and acetylcholine systems in the monkey brain (Cebus Apella). Effects of
stress. Acta Physiol Scand Suppl. 1984;534:1-27. PubMed PMID: 6150601.


33: Aquilonius SM, Eckernäs SA, Hartvig P, Lindström B, Osterman PO, Stålberg E.
Clinical pharmacology of pyridostigmine and neostigmine in patients with
myasthenia gravis. J Neurol Neurosurg Psychiatry. 1983 Oct;46(10):929-35. PubMed
PMID: 6644317; PubMed Central PMCID: PMC1027607.


34: Gottfries CG, Adolfsson R, Aquilonius SM, Carlsson A, Eckernäs SA, Nordberg
A, Oreland L, Svennerholm L, Wiberg A, Winblad B. Biochemical changes in dementia
disorders of Alzheimer type (AD/SDAT). Neurobiol Aging. 1983 Winter;4(4):261-71.
PubMed PMID: 6200784.


35: Askmark H, Aquilonius SM, Fawcett P, Nordberg A, Eckernäs SA. Acetylcholine
synthesizing activity and nicotinic binding sites in rat hind limb muscles during
reinnervation. Acta Physiol Scand. 1982 Dec;116(4):429-35. PubMed PMID: 7171002.


36: Gillberg PG, Aquilonius SM, Eckernäs SA, Lundqvist G, Winblad B. Choline
acetyltransferase and substance P-like immuno-reactivity in the human spinal
cord: changes in amyotrophic lateral sclerosis. Brain Res. 1982 Nov
4;250(2):394-7. PubMed PMID: 6184125.


37: Aquilonius SM, Askmark H, Eckernäs SA, Nordberg A. Effect of denervation on
acetylcholine synthesizing activity and nicotine-like binding sites in rat hind
limb muscles. Acta Physiol Scand. 1982 Mar;114(3):345-50. PubMed PMID: 7136765.


38: Aquilonius SM, Eckernäs SA, Gillberg PG. Topographical localization of
choline acetyltransferase within the human spinal cord and a comparison with some
other species. Brain Res. 1981 May 4;211(2):329-40. PubMed PMID: 7237127.


39: Aquilonius SM, Eckernäs SA, Hartvig P, Lindström B, Osterman PO.
Pharmacokinetics and oral bioavailability of pyridostigmine in man. Eur J Clin
Pharmacol. 1980 Nov;18(5):423-8. PubMed PMID: 7439266.


40: Eckernäs SA, Sahlström L, Aquilonius SM. Effects of atropine treatment on
cortical, striatal and hippocampal high-affinity uptake of choline in the mouse.
Life Sci. 1980 Aug 25;27(8):641-5. PubMed PMID: 7412492.


41: Eckernäs SA, Bohlin L, Sahlström L. Inhibition of brain synaptosomal uptake
of choline by some 2-carboxamidostrychnine derivatives with muscle-relaxant
properties. Acta Pharmacol Toxicol (Copenh). 1980 Aug;47(2):81-3. PubMed PMID:
7435200.


42: Aquilonius SM, Eckernäs SA, Hartvig P, Hultman J, Lindström B, Osterman PO. A
pharmacokinetic study of neostigmine in man using gas chromatography-mass
spectrometry. Eur J Clin Pharmacol. 1979 Jun 12;15(5):367-71. PubMed PMID:
456409.


43: Eckernäs SA, Mäepea O, Sahlström L, Aquilonius SM. Choline acetyltransferase
activity in human blood and its diurnal oscillation--an artifact? Med Biol. 1979
Feb;57(1):36-8. PubMed PMID: 35718.


44: Eckernäs SA, Sahlström L, Aquilonius SM. In vivo turnover rate of
acetylcholine in rat brain parts at elevated steady-state concentration of plasma
choline. Acta Physiol Scand. 1977 Dec;101(4):404-10. PubMed PMID: 596215.


45: Aquilonius SM, Eckernas SA. Choline therapy in Huntington chorea. Neurology.
1977 Sep;27(9):887-9. PubMed PMID: 142929.


46: Eckernäs SA, Aquilonius SM. A simple radioenzymatic procedure for the
determination of choline and acetylcholine in brain regions of rats sacrificed by
microwave irradiation. Acta Physiol Scand. 1977 Aug;100(4):446-51. PubMed PMID:
906850.


47: Eckernäs SA, Aquilonius SM. Free choline in human plasma analysed by simple
radio-enzymatic procedure: age distribution and effect of a meal. Scand J Clin
Lab Invest. 1977 Apr;37(2):183-7. PubMed PMID: 616044.


48: Eckernäs SA. Plasma choline and cholinergic mechanisms in the brain. Methods,
function, and rôle in Huntington's chorea. Acta Physiol Scand Suppl.
1977;449:1-62. PubMed PMID: 143869.


49: Aquilonius SM, Eckernäs SA. Cortical and striatal in vivo uptake and
metabolism of plasma choline in the rat: effects of haloperidol and apomorphine.
Acta Pharmacol Toxicol (Copenh). 1976 Jul;39(1):129-40. PubMed PMID: 988965.


50: Aquilonius SM, Eckernäs SA. Choline acetyltransferase in human cerebrospinal
fluid: non-enzymatically and enzymatically catalysed acetylcholine synthesis. J
Neurochem. 1976 Jul;27(1):317-8. PubMed PMID: 956842.


51: Aquilonius SM, Eckernäs SA. Letter: Plasma concentration of free choline in
patients with Huntington's chorea on high doses of choline chloride. N Engl J
Med. 1975 Nov 20;293(21):1105-6. PubMed PMID: 126381.


52: Aquilonius SM, Eckernås SA, Sundwall A. Regional distribution of choline
acetyltransferase in the human brain: changes in Huntington's chorea. J Neurol
Neurosurg Psychiatry. 1975 Jul;38(7):669-77. PubMed PMID: 125784; PubMed Central
PMCID: PMC1083246.